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Applying type I PRMT inhibitor GSK3368715 can inhibit PRMTS-mediated epigenetic modification of IFN genes, increase the response of IFN genes to immune signals, and reduce the expression of VEGF in immunosuppressive cells

The respective response rates according with the different initial treatments were: Ganciclovir 76% CR and 12% PR, Foscarnet 76% CR and 10% PR and Valganciclovir 90% CR and 10% PR

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